dbGaP Study Accession: phs000622.v1.p1
Principal Investigator: Richard Spritz, MD. University of Colorado School of Medicine, Aurora, CO USA
Funding Source: U01-DE020054. Genetic Determinants of Orofacial Shape and Relationship to Cleft Lip/Palate. National Institutes of Health, Bethesda, MD, USA

The goals of this project are to identify loci that underlie major genetic determinants of orofacial shape, by means of a GWAS in a cohort of normal African children (from Tanzania) from whom we have collected 3D digitized facial morphometric scans, and a subsequent replication study of normal children from the same population. These studies are part of the NIDCR FaceBase initiative (https://www.facebase.org/). In addition to dbGaP, all study genotype and phenotype data (including primary facial scans and landmarks) will be available for data-sharing with qualified investigators via the NIDCR FaceBase Hub (www.facebase.org/), following approval by the NIDCR FaceBase Data Access Committee.


Phenotypic methodology for this study can be found on PubMed.

Genotypic methodology can be found on dbGap.

Analysis methods coming soon.

Descriptive Statistics

Explore Project Data

Data for this project is coming soon!


PubMed list for all publications associated with grant number U01-DE020054.